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A dose-finding approach based on shrunken predictive probability for combinations of two agents in phase I trials

Akihiro Hirakawa1, Chikuma Hamada, Shigeyuki Matsui

  • 1Center for Advanced Medicine and Clinical Research, Nagoya University Graduate School of Medicine, Aichi, 466-8560, Japan.

Statistics in Medicine
|May 8, 2013
PubMed

Keywords:
combinationdose-finding studiesphase I trialpredictionshrinkage

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