Related Experiment Video

Updated: May 11, 2026

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors
08:45

Assessing Cellular Target Engagement by SHP2 (PTPN11) Phosphatase Inhibitors

Published on: July 17, 2020

How does SHIP1/2 balance PtdIns(3,4)P2 and does it signal independently of its phosphatase activity?

Jingwei Xie1, Christophe Erneux, Isabelle Pirson

  • 1Department of Pathophysiology, China Medical University, Heping District, Shenyang Liaoning Province, China.

Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology
|May 8, 2013
PubMed

Keywords:
EGFR endocytosisPtdIns(3,4)P2SHIP1/2mono-ubiquitinationscaffold properties

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