Is applying the same exercise-based inpatient program to normal and reduced left ventricular function patients the

Renata Gonçalves Mendes1, Rodrigo Polaquini Simões, Fernando de Souza Melo Costa

  • 1Cardiopulmonary Physiotherapy Laboratory, Nucleus of Research in Physical Exercise, Federal University of Sao Carlos , Sao Paulo , Brazil .

Insights

Patients undergoing coronary artery bypass graft (CABG) surgery showed different cardiac autonomic responses to inpatient exercise programs based on left ventricular function (LVF). Reduced LVF led to a more pronounced response, suggesting tailored exercise prescriptions post-CABG.

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Autonomic Nervous System Function

Background:

  • Coronary artery bypass graft (CABG) surgery is a common procedure for managing coronary artery disease.
  • Left ventricular function (LVF) can be normal or reduced post-CABG, potentially influencing recovery and response to rehabilitation.
  • Cardiac autonomic response plays a crucial role in cardiovascular health and recovery after cardiac surgery.

Purpose of the Study:

  • To compare the cardiac autonomic response to a standardized inpatient exercise program in post-CABG patients with normal versus reduced left ventricular function (LVF).
  • To determine if the same exercise protocol elicits similar autonomic adjustments in these two patient groups.

Main Methods:

  • Forty-four post-CABG patients were divided into normal LVF (LVFN) and reduced LVF (LVFR) groups based on left ventricular ejection fraction (LVEF).
  • An inpatient progressive exercise program was initiated on post-operative day 1 (PO1) and continued until discharge.
  • Heart rate variability (HRV) indices were measured at rest and during exercise (range of motion, ambulation) to assess cardiac autonomic response.

Main Results:

  • During ambulation, patients with reduced LVF (LVFR) exhibited significantly lower heart rate variability (HRV) indices compared to those with normal LVF (LVFN).
  • The change in HRV from rest to ambulation was also attenuated in the LVFR group for both linear and non-linear HRV measures.
  • On PO1, only intra-group differences between rest and exercise were observed for heart rate parameters.

Conclusions:

  • The same inpatient exercise protocol resulted in a more attenuated cardiac autonomic response in post-CABG patients with normal LVF compared to those with reduced LVF.
  • These findings highlight the importance of tailoring inpatient exercise volume based on individual left ventricular function in the early recovery phase after CABG.
  • Prescribing exercise according to LVF is crucial for optimizing rehabilitation outcomes in post-CABG patients.
Abstract

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