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Is applying the same exercise-based inpatient program to normal and reduced left ventricular function patients the
Renata Gonçalves Mendes1, Rodrigo Polaquini Simões, Fernando de Souza Melo Costa
1Cardiopulmonary Physiotherapy Laboratory, Nucleus of Research in Physical Exercise, Federal University of Sao Carlos , Sao Paulo , Brazil .
Insights
Patients undergoing coronary artery bypass graft (CABG) surgery showed different cardiac autonomic responses to inpatient exercise programs based on left ventricular function (LVF). Reduced LVF led to a more pronounced response, suggesting tailored exercise prescriptions post-CABG.
Area of Science:
- Cardiology
- Exercise Physiology
- Autonomic Nervous System Function
Background:
- Coronary artery bypass graft (CABG) surgery is a common procedure for managing coronary artery disease.
- Left ventricular function (LVF) can be normal or reduced post-CABG, potentially influencing recovery and response to rehabilitation.
- Cardiac autonomic response plays a crucial role in cardiovascular health and recovery after cardiac surgery.
Purpose of the Study:
- To compare the cardiac autonomic response to a standardized inpatient exercise program in post-CABG patients with normal versus reduced left ventricular function (LVF).
- To determine if the same exercise protocol elicits similar autonomic adjustments in these two patient groups.
Main Methods:
- Forty-four post-CABG patients were divided into normal LVF (LVFN) and reduced LVF (LVFR) groups based on left ventricular ejection fraction (LVEF).
- An inpatient progressive exercise program was initiated on post-operative day 1 (PO1) and continued until discharge.
- Heart rate variability (HRV) indices were measured at rest and during exercise (range of motion, ambulation) to assess cardiac autonomic response.
Main Results:
- During ambulation, patients with reduced LVF (LVFR) exhibited significantly lower heart rate variability (HRV) indices compared to those with normal LVF (LVFN).
- The change in HRV from rest to ambulation was also attenuated in the LVFR group for both linear and non-linear HRV measures.
- On PO1, only intra-group differences between rest and exercise were observed for heart rate parameters.
Conclusions:
- The same inpatient exercise protocol resulted in a more attenuated cardiac autonomic response in post-CABG patients with normal LVF compared to those with reduced LVF.
- These findings highlight the importance of tailoring inpatient exercise volume based on individual left ventricular function in the early recovery phase after CABG.
- Prescribing exercise according to LVF is crucial for optimizing rehabilitation outcomes in post-CABG patients.
Purpose:
To assess whether the same exercise-based inpatient program applied to patients with normal and reduced left ventricular function (LVF) evokes a similar cardiac autonomic response after coronary artery bypass graft (CABG).
Method:
Forty-four patients post-CABG, subgrouped according to normal LVF [LVFN: n = 23; left ventricular ejection fraction (LVEF) ≥ 55%] and reduced LVF (LVFR: n = 21; LVEF 35-54%), were included. All initiated the exercise protocol on post-operative day 1 (PO1), following a whole progressive program until discharge. Cardiac autonomic response was assessed by the indices of heart rate variability (HRV) at rest and during exercise (extremity range of motion and ambulation).
Results:
During ambulation, lower values of HRV indices were found in the LVFR group compared with the LVFN group [standard deviation of all RR (STDRR; 6.1 ± 2.7 versus 8.9 ± 4.7 ms), baseline width of the RR histogram (TINN; 30.6 ± 14.8 versus 45.8 ± 24.9 ms), SD2 (14.8 ± 8.0 versus 21.3 ± 9.0 ms), Shannon entropy (3.6 ± 0.5 versus 3.9 ± 0.4) and correlation dimension (0.08 ± 0.2 versus 0.2 ± 0.2)]. Also, when comparing the ambulation to rest change, lower values were observed in the LVFR group for linear (STDRR, TINN, RR TRI, rMSSD) and non-linear (SD2 and correlation dimension) HRV indices (p < 0.05). On PO1, we observed only intra-group differences between rest and exercise (extremity range of motion), for mean intervals between heart beats and heart rate.
Conclusion:
For patients with LVFN, the same inpatient exercise protocol triggered a more attenuated autonomic response compared with patients with LVFR. These findings have implications as to how exercise should be prescribed according to LVF in the early stages following recovery from CABG. Implications for Rehabilitation Exercise-based inpatient program, performed by post-CABG patients who have normal left ventricular function, triggered a more attenuated cardiac autonomic response compared with patients with reduced left ventricular function. Volume of the inpatient exercises should be prescribed according to the left ventricular function in the early stages following recovery from CABG.
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