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Updated: May 11, 2026

Surgical Transplantation of Tumor Cells into the Spinal Cord of Mice
Published on: December 27, 2024
[Glioblastoma multiforme with intra- and extramedullary dissemination to the spinal cord]
Karin Hansson1, Henrik Gutte, Fadi Idris
1Radiologisk Afsnit, Diagnostisk Afdeling, Glostrup Hospital, Nordre Ringvej 57, 2600 Glostrup, Denmark. karin.hansson.lundblad@gmail.com
Abstract:
Metastases to the spinal cord from glioblastoma multiforme (GBM) are uncommon, but important to have in mind when patients with a history of GBM present with symptoms that do not correlate with the primary disease pattern. We report a rare case, where a male with GBM, six months after tumour excision followed by concomitant radio- and chemotherapy, presented with gait disturbance and unspecific neurological symptoms of the lower right limb. Magnetic resonance imaging of columna totalis revealed both intra- and extramedullary metastases in the spinal cord. The patient died one month later.

