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Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Effects on the photon beam from an electromagnetic array used for patient localization and tumor tracking
Wei Zou1, Ricardo Betancourt, Lingshu Yin
1Department of Radiation Oncology, Cancer Institute of New Jersey, New Brunswick, NJ 08903, USA. weizou@sas.upenn.edu
Journal of Applied Clinical Medical Physics
|May 9, 2013
Summary
The Calypso electromagnetic array causes minimal beam attenuation (<3%) and insignificant dose spoiling beyond the buildup region during radiation therapy. Its use in intensity-modulated radiation therapy (IMRT) and volumetric modulated arc therapy (VMAT) plans results in clinically insignificant dose differences.
Area of Science:
- Medical Physics
- Radiation Oncology
- Medical Imaging
Background:
- The Calypso 4D localization and tracking system uses an electromagnetic array for real-time target monitoring during radiation therapy.
- Understanding the array's impact on radiation beams is crucial for treatment accuracy.
Purpose of the Study:
- To investigate the beam attenuation and beam spoiling properties of the Calypso electromagnetic array.
- To assess the clinical significance of dose differences introduced by the array.
Main Methods:
- Measurements were conducted using 6 MV and 15 MV photon beams on a Varian Clinac iX linear accelerator.
- Narrow and broad beam attenuation were measured using a photon diode and Farmer chamber, respectively.
- Beam spoiling was assessed by measuring depth-dose changes at various distances with an embedded Markus parallel plate chamber.
Main Results:
- Beam attenuation was less than 2%-3% for angles <40° and increased at more oblique angles.
- Spoiling effects were significant in the buildup region but negligible beyond the maximum dose depth (dmax).
- Dose differences in IMRT and VMAT plans were less than 2.5%.
Conclusions:
- The Calypso electromagnetic array exhibits minimal beam attenuation and dose spoiling effects.
- The observed dose differences are clinically insignificant, supporting its use in radiation therapy monitoring.

