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Concurrent septic arthritis and osteomyelitis in children
Corey O Montgomery1, Eric Siegel, Robert D Blasier
1Department of Orthopaedics, Center for Orthopaedic Research, University of Arkansas Medical Sciences, Little Rock, AR 72205, USA. comontgomery@uams.edu
Insights
Concurrent infections (CI) of septic arthritis and osteomyelitis are common in newborns and adolescents, particularly in the shoulder. Early diagnosis using advanced imaging can reduce hospital stays and surgical procedures.
Area of Science:
- Orthopedics
- Infectious Diseases
- Radiology
Background:
- Septic arthritis and osteomyelitis are serious conditions that can occur together.
- Delayed diagnosis of concurrent infections (CI) can lead to worse outcomes.
Purpose of the Study:
- To identify factors aiding earlier diagnosis of concurrent infections (CI) in patients with septic arthritis.
Main Methods:
- Retrospective chart review of 200 patients with septic arthritis.
- Comparison of patients with CI versus septic arthritis alone using statistical tests.
Main Results:
- 21.5% of patients had CI.
- CI were most prevalent in newborns and adolescents (P<0.0001) and shoulder infections (72%, P<0.0001).
- CI correlated with longer symptom duration (median 6 days), longer hospital stays (median 6 days), more operations, and higher ICU admission rates.
Conclusions:
- Advanced imaging (CT, bone scan, MRI) is recommended for patients with septic arthritis who are neonates, adolescents (13-20 years), have shoulder involvement, or symptoms >6 days.
- Early identification of CI can potentially reduce hospital stays, operative procedures, and infection-related complications.
Introduction:
Septic arthritis and osteomyelitis can both independently cause substantial morbidity. With concomitant septic arthritis and osteomyelitis, the septic arthritis may be treated without knowledge of the adjacent osteomyelitis resulting in delayed treatment. This study aims to identify factors that may help to diagnosis concurrent infections (CI) earlier.
Methods:
A retrospective chart review of 200 patients with septic arthritis was performed. Patients with CI were compared with patients with septic arthritis alone using tests determined by the nature of the variable being analyzed (the χ test, the Fisher exact test, the Cochran-Armitage trend test, and the Kruskal-Wallis test.).
Results:
Two hundred patients were eligible and analyzed, of which 43 (21.5%) had CI. On the basis of age, CI were most common in newborns and adolescents (P<0.0001). On the basis of location, 72% of shoulder infections (P<0.0001) were concurrent, whereas <50% of elbows, hips, knees, and ankle were CI. The most common infective organism was methicillin-sensitive Staphylococcus aureus (P<0.0001). CI were significantly associated with increased median (6) days of clinical symptoms before presentation (P<0.0001), increased duration of median (6) days of hospital stay (P<0.0001), increased number of operative procedures (P=0.005), and increased need for ICU admission (P=0.024).
Conclusions:
Utilizing advanced imaging (CT scan, bone scan, and/or MRI) in patients with septic arthritis who are younger than 4 months of age, between ages 13 and 20 years, with septic arthritis involving the shoulder, and with symptoms for more than 6 days may shorten hospital stays, decrease the number of operative procedures required, and possibly limit infection-related sequelae by identifying CI earlier.
Level Of Evidence:
III.
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