AdipoQ polymorphisms are associated with type 2 diabetes mellitus: a meta-analysis study

Haiyan Chu1, Meilin Wang, Dongyan Zhong

  • 1State Key Laboratory of Reproductive Medicine, Institute of Toxicology, Nanjing Medical University, Nanjing, China; Department of Environmental Genomics, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Cancer Center, Nanjing Medical University, Nanjing, China; Department of Genetic Toxicology, the Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing, China.

Summary

This meta-analysis found that the adiponectin -11426A > G polymorphism is associated with an increased risk of type 2 diabetes mellitus (T2DM). This genetic variation may contribute to T2DM pathogenesis in European and Asian populations.

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