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Updated: May 11, 2026

Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Classifying the reasons men consider to be important in prostate-specific antigen (PSA) testing decisions: evaluating
Michelle E McDowell1, Stefano Occhipinti, Suzanne K Chambers
1Griffith Health Institute, School of Applied Psychology, Griffith University, Mount Gravatt, QLD, 4111, Australia, M.McDowell@griffith.edu.au.
Background:
Despite uncertainty regarding the benefits of prostate cancer screening, many men have had a prostate-specific antigen (PSA) test.
Purpose:
This study aims to identify classes of reasons guiding men's decisions about prostate cancer screening and predict reasoning approaches by family history and prior screening behaviour.
Methods:
First-degree relatives of men with prostate cancer (n = 207) and men from the general population (n = 239) of Australia listed reasons they considered when deciding whether to have a PSA test.
Results:
Responses were coded into 31 distinct categories. Latent class analysis identified three classes. The evaluation of risk information cues class (20.9 %) contained a greater number of men with a family history (compared with control and overcome cancer/risk class; 52.7 %). Informed decisions and health system class (26.5 %) included a lower proportion of men who had had a PSA test and greater proportions of highly educated and married men.
Conclusion:
Understanding the reasons underlying men's screening decisions may lead to a more effective information provision and decision support.
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