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Related Concept Videos

Structure and Function of Platelets01:18

Structure and Function of Platelets

The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000 platelets, with...

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Updated: May 11, 2026

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor
06:32

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Published on: May 2, 2025

State of the art in platelet function testing.

Beate E Kehrel1, Martin F Brodde

  • 1Department of Anesthesiology, Intensive Care and Pain Medicine, Experimental and Clinical Hemostasis, University of Münster, Germany.

Transfusion Medicine and Hemotherapy : Offizielles Organ Der Deutschen Gesellschaft Fur Transfusionsmedizin Und Immunhamatologie
|May 9, 2013
PubMed
Summary
This summary is machine-generated.

Platelet function tests are crucial for diagnosing bleeding disorders and monitoring therapies. This review covers applications and diverse methods for assessing platelet activity.

Keywords:
Antiplatelet drugsPlatelet concentratesPlatelet disordersPlatelet function testing

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Microfluidics in Assessing Platelet Function
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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
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A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

Related Experiment Videos

Last Updated: May 11, 2026

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor
06:32

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Published on: May 2, 2025

Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time
09:38

A Microfluidic Flow Chamber Model for Platelet Transfusion and Hemostasis Measures Platelet Deposition and Fibrin Formation in Real-time

Published on: February 14, 2017

Area of Science:

  • Hematology
  • Clinical Pathology
  • Biomedical Science

Background:

  • Platelets are vital for hemostasis and play roles in various physiological and pathological processes.
  • Numerous platelet function tests have been developed for specific diagnostic and monitoring purposes.

Purpose of the Study:

  • To review the current applications of platelet function testing.
  • To outline the various methodologies available for assessing platelet function.

Main Methods:

  • The review covers diagnostic fields including bleeding disorders, anti-platelet therapy monitoring, transfusion medicine, and perioperative bleeding prediction.
  • Methods discussed include bleeding time, platelet counting, adhesion, secretion, aggregation, morphology, signal transduction, procoagulant activity, apoptosis, proteomics, and molecular biology.

Main Results:

  • Platelet function testing is applied across diverse clinical scenarios, from diagnostics to therapeutic monitoring.
  • A wide array of techniques exist, ranging from traditional assays to advanced molecular and proteomic analyses.

Conclusions:

  • Comprehensive platelet function testing is essential for accurate diagnosis and effective management in various clinical settings.
  • Understanding the spectrum of available tests and their applications is key for optimizing patient care.