Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Inflammatory Bowel Disease II: Ulcerative Colitis01:20

Inflammatory Bowel Disease II: Ulcerative Colitis

Ulcerative colitis is a chronic inflammatory disorder of the colon characterized by continuous mucosal inflammation that typically begins in the rectum and extends proximally in a uniform pattern. Its pathogenesis involves a complex interplay of genetic predisposition, immune dysregulation, and environmental influences. These factors converge to impair the colon’s epithelial defenses and promote an exaggerated inflammatory response against luminal contents.Breakdown of the Mucosal BarrierA...
Histology of the Small Intestine01:27

Histology of the Small Intestine

The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Role of Angiotensin II as a Vasoactive Agent to Treat Distributive Shock With a Focus on Preliminary Data in Pediatric-Aged Patients.

Paediatric anaesthesia·2026
Same author

Association of Total Body Fat Percentiles, Obesity and Cardiometabolic Health Biomarkers in Adults in the United States.

Obesity science & practice·2026
Same author

Technology-enhanced studio design and creative musicianship: Exploring self-efficacy and motivational moderators.

Acta psychologica·2026
Same author

Socioeconomic and Clinical Determinants Driving Access to BRCA Genetic Testing in Cancer : A Case-Control Study Using Observational Electronic Health Records Across Multiple Sites.

medRxiv : the preprint server for health sciences·2026
Same author

Reading between the lists: Trends and decisions in delisting for clinical improvement.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·2026
Same author

Survival in de novo perihilar cholangiocarcinoma: Does transplant outperform resection?

Hepatology (Baltimore, Md.)·2026
Same journal

Delayed-Onset Cefepime Neurotoxicity in a Patient With Epilepsy and ESRD.

Case reports in medicine·2026
Same journal

Fatal Rhinocerebral Mucormycosis and <i>Aspergillus flavus</i> Coinfection Complicated by Internal Carotid Artery Arteritis: A Case Report.

Case reports in medicine·2026
Same journal

A Case of Strabismus in a Patient With Psoriasis.

Case reports in medicine·2026
Same journal

Acute Right Ventricular Failure Triggered by Excessive Fluid Resuscitation in Septic Shock.

Case reports in medicine·2026
Same journal

Tourniquet-Induced Atypical Lower Back Pain Under Spinal Anesthesia: A Case Report and Mechanistic Exploration of Referred Pain.

Case reports in medicine·2026
Same journal

Paroxysmal Atrial Tachycardia With Atrioventricular Block: A Report of Two Cases.

Case reports in medicine·2026
See all related articles

Related Experiment Video

Updated: May 11, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Microscopic colitis with macroscopic endoscopic findings.

Atif Saleem1, Parag A Brahmbhatt, Sarah Khan

  • 1Division of Gastroenterology and Hepatology, Department of Internal Medicine, East Tennessee State University, P.O. Box 70622, Johnson City, TN 37614, USA.

Case Reports in Medicine
|May 9, 2013
PubMed
Summary
This summary is machine-generated.

Microscopic colitis typically shows normal endoscopic views but inflammation on biopsy. This case highlights collagenous colitis presenting with visible endoscopic abnormalities.

More Related Videos

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
07:05

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation

Published on: December 15, 2017

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Related Experiment Videos

Last Updated: May 11, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
09:42

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation

Published on: August 26, 2014

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation
07:05

Fluorescence-mediated Tomography for the Detection and Quantification of Macrophage-related Murine Intestinal Inflammation

Published on: December 15, 2017

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
15:49

Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System

Published on: October 16, 2013

Area of Science:

  • Gastroenterology
  • Pathology

Background:

  • Microscopic colitis (MC) causes chronic watery diarrhea with normal-appearing colonic mucosa on endoscopy.
  • Diagnosis relies on identifying microscopic inflammation and characteristic changes in colon biopsies.

Purpose of the Study:

  • To report a rare case of collagenous colitis.
  • To describe collagenous colitis with unusual gross endoscopic findings.

Main Methods:

  • Case report review.
  • Endoscopic examination of the colon.
  • Histopathological analysis of colon biopsies.

Main Results:

  • The patient presented with chronic watery diarrhea.
  • Colonoscopy revealed gross abnormalities not typically seen in microscopic colitis.
  • Biopsies confirmed collagenous colitis.

Conclusions:

  • Collagenous colitis can occasionally present with visible endoscopic abnormalities.
  • This case expands the endoscopic spectrum of microscopic colitis.