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Updated: May 11, 2026

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

Assessing student understanding of host pathogen interactions using a concept inventory.

Gili Marbach-Ad¹, Volker Briken, Najib M El-Sayed

¹Department of Cell Biology and Molecular Genetics, College of Chemical and Life Sciences, University of Maryland, College Park, Maryland 20742.

Journal of Microbiology & Biology Education

|May 9, 2013

Summary

Faculty developed a host-pathogen interactions (HPI) concept inventory to assess student learning in microbiology. The tool revealed retained knowledge in advanced courses and improvement in some, guiding future curriculum development.

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Area of Science:

Microbiology Education
Host-Pathogen Interactions (HPI)

Background:

Faculty expertise in host-pathogen interactions (HPI) prompted a focus on student comprehension of HPI concepts.
Existing microbiology courses had significant content overlap, hindering progressive concept development.

Purpose of the Study:

To develop and implement a concept inventory for assessing student understanding of host-pathogen interactions (HPI).
To measure student learning progression across a sequence of microbiology courses.
To inform curriculum development by identifying concept retention and areas for improvement.

Main Methods:

Development of an 18-question, multiple-choice concept inventory focused on HPI.
Administration of the inventory as pre- and post-course surveys to 477 students across six microbiology courses.
Analysis of survey data collected in Fall 2006 and Spring 2007.

Main Results:

Students in advanced courses demonstrated retention of HPI knowledge from prerequisite general microbiology courses.
Significant score improvements were observed from pretest to posttest in two of the evaluated courses.
The inventory provided insights into student learning progression in HPI.

Conclusions:

The developed HPI concept inventory is a viable tool for assessing student learning in microbiology.
Curriculum adjustments may be needed to optimize concept progression and address learning gaps.
Further exploration of HPI concepts across courses will refine teaching methods for meaningful student learning.