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Related Experiment Videos

Lymphocytic-plasmacytic enteritis in two horses.

C G MacAllister1, D Mosier, C W Qualls

  • 1Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, Oklahoma State University, Stillwater 74078.

Journal of the American Veterinary Medical Association
|June 15, 1990
PubMed
Summary

Chronic weight loss in horses can signal serious intestinal issues. Lymphocytic and plasmacytic infiltration of the intestine causes malabsorption and protein-losing enteropathy in horses.

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Area of Science:

  • Veterinary Medicine
  • Gastroenterology
  • Hematology

Background:

  • Chronic weight loss is a common presenting complaint in equine medicine.
  • Understanding the underlying causes is crucial for effective treatment.
  • Small intestinal dysfunction can lead to significant nutritional deficits.

Observation:

  • Two adult horses presented with chronic weight loss.
  • Hematologic abnormalities included hypoalbuminemia and hyperglobulinemia.
  • One horse exhibited anemia, subclinical disseminated intravascular coagulation, and prolonged sulfobromophthalein half-life.

Findings:

  • Abnormal D-xylose absorption tests indicated small intestinal dysfunction and malabsorption.
  • Clinicopathologic and pathologic findings supported a diagnosis of malabsorption and protein-losing enteropathy.

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  • The condition was attributed to lymphocytic and plasmacytic infiltration of the intestinal lining.

    • Implications:

    • This study highlights a specific cause of malabsorption and protein-losing enteropathy in horses.
    • Early diagnosis and targeted treatment are essential for horses with these clinical signs.
    • Further research into the etiology of intestinal lymphocytic and plasmacytic infiltration is warranted.