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Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
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Macrostomia: a spectrum of deformity

Samuel Buonocore1, P Niclas Broer, Marc E Walker

  • 1From the *Section of Plastic and Reconstructive Surgery, Department of Surgery, Yale University School of Medicine, New Haven, CT; †Plastic and Reconstructive Surgery Unit, Federal University of Paraná; ‡Assistance Center for Cleft Lip and Palate, Curitiba, Parana; §Plastic Surgery Center of the Federal University of Rio de Janeiro, Rio de Janeiro; and ∥The Craniofacial Surgery Unit, Department of Plastic Surgery, São Paulo University, São Palo, Brazil.

Annals of Plastic Surgery
|May 10, 2013
PubMed
Summary

Macrostomia, a rare facial cleft, presents with diverse phenotypes, suggesting multiple causes. Isolated cases indicate intrauterine trauma or abnormal FGF8 function impacting facial development.

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