Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imbalances in Cardiac Output01:26

Imbalances in Cardiac Output

The heart's primary function is to pump blood throughout the body, maintaining a balance between blood sent out (cardiac output) and blood returning (venous return). If this balance is disrupted, it can result in congestive heart failure (CHF), a severe condition where the heart becomes an inefficient pump, leading to inadequate blood circulation.
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Exercise Stress Test01:26

Exercise Stress Test

Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
Exercise and Cardiovascular Response01:20

Exercise and Cardiovascular Response

Exercise significantly impacts cardiovascular response, which is crucial for understanding patient health and designing effective treatment plans.
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Mitral Regurgitation I: Introduction01:20

Mitral Regurgitation I: Introduction

Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility, Safety and Outcomes of Early Mobilization in the ICU Following Lung Transplantation: A Scoping Review.

Clinical transplantation·2026
Same author

Comparison of venous morphology, chronic venous disease stage and venous symptoms in high-impact activities versus low-impact activities.

Journal of vascular surgery. Venous and lymphatic disorders·2026
Same author

Determinants of childhood and adolescent obesity: An explainable AI approach using the ICAD database.

Public health·2026
Same author

Clinical Significance of Using Stress Echocardiography for Cardiovascular Rehabilitation.

Journal of visualized experiments : JoVE·2026
Same author

Identifying a fitness tool in early old-age to predict long-term risk of disability, severe disability, and mortality.

GeroScience·2026
Same author

Heat Acclimation with Blood Flow Restriction Improves Cognitive-Motor Dual-Task Ability and Neuromuscular Fatigue.

Scandinavian journal of medicine & science in sports·2026

Related Experiment Video

Updated: May 11, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Depressed systolic function after a prolonged and strenuous exercise.

Damien Vitiello1, Johan Cassirame, Arnaud Menetrier

  • 11EA-4278, Pharm-Ecologie Cardiovasculaire, Faculty of Sciences, University of Avignon, Avignon, FRANCE; 2EA-3920, Physiopathologie cardiovasculaire et prévention, Faculty of Sport Sciences, University of Franche Comté, Besançon, FRANCE; 3HP2 Laboratory (INSERM), Joseph Fourier University and Exercise Research Unit, University Hospital, Grenoble, FRANCE; and 4Department of Vascular Medicine, Nimes University Hospital, Nimes, FRANCE.

Medicine and Science in Sports and Exercise
|May 10, 2013
PubMed
Summary
This summary is machine-generated.

Prolonged strenuous exercise (PSE) causes temporary left ventricular (LV) systolic dysfunction, particularly evident during incremental tests. This dysfunction was observed even after heart rate returned to normal levels post-exercise.

More Related Videos

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
12:37

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Published on: February 9, 2016

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
10:08

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

Related Experiment Videos

Last Updated: May 11, 2026

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans
07:26

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

Published on: October 17, 2018

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine
12:37

Surgical Placement of Catheters for Long-term Cardiovascular Exercise Testing in Swine

Published on: February 9, 2016

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
10:08

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine

Published on: February 17, 2018

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Echocardiography

Background:

  • Prolonged and strenuous exercise (PSE) can cause transient left ventricular (LV) dysfunction.
  • The impact of PSE on LV systolic function is debated, potentially due to exercise-induced heart rate and loading condition changes.
  • Assessing LV systolic function requires methods that account for heart rate variations.

Purpose of the Study:

  • To evaluate changes in LV systolic function before and after PSE.
  • To utilize two-dimensional speckle tracking echocardiography (2DSTE) for precise measurements.
  • To differentiate between resting and exercise-induced effects on systolic function by incorporating incremental tests.

Main Methods:

  • Sixteen healthy young men underwent a 3-hour controlled cycling exercise protocol.
  • LV strain, systolic strain rate (SR), rotation, and rotational rate were measured using 2DSTE.
  • Measurements were taken at rest and during incremental exercise tests, both before and after the PSE, with post-exercise evaluation occurring after heart rate normalized.

Main Results:

  • At rest, LV systolic function parameters were unchanged or improved post-PSE.
  • During incremental exercise tests, significant decreases were observed in LV systolic SR and apical rotational rates after PSE.
  • Regression analysis indicated a reduction in both global and regional LV systolic function, independent of heart rate, following the exercise period.

Conclusions:

  • Three hours of PSE induces LV systolic dysfunction.
  • This dysfunction is detectable during incremental exercise testing, even when heart rate has normalized.
  • The findings highlight the detrimental effects of prolonged strenuous exercise on cardiac systolic performance.