The spectrum of cerebral visual impairment as a sequel to premature birth: an overview

Gordon N Dutton1

  • 1Department of Visual Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G4 0BA, UK. dutton@duttonhome.com

Insights

Vision impairment in premature children often stems from brain damage, not just retinopathy. Early diagnosis of cerebral visual impairment is crucial for optimal development and support at home and school.

Area of Science:

  • Neuroscience
  • Ophthalmology
  • Developmental Pediatrics

Background:

  • Vision impairment in premature infants is frequently caused by brain damage, surpassing retinopathy of prematurity.
  • Cerebral visual impairment (CVI) diagnosis in this population is often overlooked.
  • Premature birth is a significant risk factor for acquired brain injury leading to visual deficits.

Purpose of the Study:

  • To review cerebral visual impairment in children born prematurely.
  • To elucidate the types of visual deficits and associated behaviors resulting from premature birth.
  • To raise awareness regarding the diagnosis and management of CVI in preterm infants.

Main Methods:

  • Comprehensive literature review utilizing PubMed as the primary data source.
  • Synthesis of information on the origins and manifestations of visual deficits linked to premature birth.
  • Analysis of behavioral outcomes associated with various visual impairments.

Main Results:

  • Premature birth-related brain damage can cause a spectrum of visual deficits, including primary visual function impairments, perceptual dysfunction, and optic ataxia.
  • Disorders affecting visual attention and memory are also observed.
  • These deficits can manifest in diverse combinations and varying degrees, leading to specific behavioral outcomes.

Conclusions:

  • Accurate identification and characterization of vision impairment due to prematurity-associated brain damage are essential.
  • Timely diagnosis prevents disadvantages for affected children.
  • Optimal management at home and school enhances developmental outcomes for children with CVI.
Abstract

Related Concept Videos

Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Prosopagnosia01:24

Prosopagnosia

Prosopagnosia, also known as face blindness, is the inability to recognize faces. In severe cases, individuals with prosopagnosia may not recognize close family members, including parents and spouses, by their faces. For instance, someone with prosopagnosia might walk past their child in a crowd, only realizing their mistake upon noticing their child's distinctive backpack or favorite jacket. Prosopagnosia specifically impairs facial recognition, while the recognition of other objects or...
Cerebral Edema l: Introduction01:19

Cerebral Edema l: Introduction

Cerebral edema is a pathological increase in brain water content that disrupts intracranial pressure regulation and impairs neurological function. Because the cranial vault is rigid, even modest increases in tissue volume can compromise cerebral perfusion, distort neural structures, and initiate secondary injury. Cerebral edema develops through four principal mechanisms: vasogenic, cytotoxic, interstitial, and ionic.Vasogenic EdemaVasogenic edema arises from disruption of the blood–brain...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Traumatic Brain Injury l: Introduction01:28

Traumatic Brain Injury l: Introduction

DefinitionTraumatic brain injury, or TBI, is a disturbance of normal brain function induced by an external mechanical force, such as a direct blow to the head or a penetrating injury. It can affect both brain structure and function, producing a wide range of clinical outcomes. TBI is a heterogeneous condition, meaning its effects may differ based on the type, location, and severity of the injury.Basis of ClassificationTBI is classified based on severity, injury mechanism, or pathophysiology. In...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...