Related Experiment Video
Updated: May 11, 2026

Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
Published on: November 20, 2015
The spectrum of cerebral visual impairment as a sequel to premature birth: an overview
1Department of Visual Sciences, Glasgow Caledonian University, Cowcaddens Road, Glasgow, G4 0BA, UK. dutton@duttonhome.com
Insights
Vision impairment in premature children often stems from brain damage, not just retinopathy. Early diagnosis of cerebral visual impairment is crucial for optimal development and support at home and school.
Area of Science:
- Neuroscience
- Ophthalmology
- Developmental Pediatrics
Background:
- Vision impairment in premature infants is frequently caused by brain damage, surpassing retinopathy of prematurity.
- Cerebral visual impairment (CVI) diagnosis in this population is often overlooked.
- Premature birth is a significant risk factor for acquired brain injury leading to visual deficits.
Purpose of the Study:
- To review cerebral visual impairment in children born prematurely.
- To elucidate the types of visual deficits and associated behaviors resulting from premature birth.
- To raise awareness regarding the diagnosis and management of CVI in preterm infants.
Main Methods:
- Comprehensive literature review utilizing PubMed as the primary data source.
- Synthesis of information on the origins and manifestations of visual deficits linked to premature birth.
- Analysis of behavioral outcomes associated with various visual impairments.
Main Results:
- Premature birth-related brain damage can cause a spectrum of visual deficits, including primary visual function impairments, perceptual dysfunction, and optic ataxia.
- Disorders affecting visual attention and memory are also observed.
- These deficits can manifest in diverse combinations and varying degrees, leading to specific behavioral outcomes.
Conclusions:
- Accurate identification and characterization of vision impairment due to prematurity-associated brain damage are essential.
- Timely diagnosis prevents disadvantages for affected children.
- Optimal management at home and school enhances developmental outcomes for children with CVI.
Purpose:
In children born prematurely, impairment of vision due to damage to the brain is more common than due to retinopathy of prematurity. Yet, the diagnosis of cerebral visual impairment may be missed. The subject of cerebral visual impairment in children is reviewed in order to explain and draw attention to the types of visual deficits and behaviours that may result as a sequel to premature birth.
Methods:
A wide range of sources of data has been employed to assemble this overview. The principal reference source is PubMed.
Results:
The material presented highlights the origin and range of visual deficits that result from damage to the brain, related to premature birth. Deficits of primary visual functions, perceptual dysfunction, simultanagnostic visual disorders and impaired visual guidance of movement (optic ataxia), as well as disorders of visual attention and memory, can occur in a variety of combinations and degrees. The resulting behavioural outcomes are described.
Conclusion:
Identification and characterisation of impaired vision, due to prematurity associated damage to the brain, are essential. This is required so as to ensure that affected children are not inappropriately disadvantaged on account of the diagnosis being missed or inadequately acted upon, but instead, they are managed optimally, both at home and at school, so that their development is enhanced to the greatest advantage.
Related Concept Videos
Photoreceptors and Visual Pathways
Prosopagnosia
Cerebral Edema l: Introduction
Glaucoma: Overview
Traumatic Brain Injury l: Introduction
Cerebral Edema ll: Pathophysiology

