Related Experiment Video
Updated: Feb 10, 2026

Phospholipid Mediator Induced Transformation in Three-Dimensional Cultures
Published on: July 27, 2022
Effects of phospholipid hepatoprotectors on apoptosis during experimental liver pathology induced by isoniazid and
V V Udut1, A I Vengerovsky, A M Dygai
1Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Russia. udutv@mail.ru
Abstract:
Phospholipid hepatoprotectors essentiale, eplir, and their combinations with succinic acid decreased the relative content of apoptotic lymphocytes and granulocytes in the blood, content of TNF-α, total and indirect bilirubin, and activities of transaminases and alkaline phosphatase and increase the content of IL-10 in rats with experimental intoxication induced by isoniazid and paracetamol. A combination of eplir and succinic acid was most effective in preventing the development of leukocyte apoptosis.
More Related Videos
11:06Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
Published on: January 31, 2022
09:50Experimental Methods for Testing the Effects of Neurotrophic Peptide, ADNF-9, Against Alcohol-induced Apoptosis during Pregnancy in C57BL/6 Mice
Published on: April 24, 2013
Related Concept Videos
Apoptosis
Buffer Effectiveness
The buffer capacity is the amount of acid or base that can be added to a given volume...
Biological Effects of Radiation
Framing Effects
Liver Histology
Hepatocytes perform a variety of essential functions. They secrete...
Liver Physiology
Metabolic Regulation:
The liver is the central organ involved in regulating blood composition. It stabilizes blood glucose levels, maintaining them within the range of 70–110 mg/dL. When these levels drop, the liver breaks down glycogen reserves and releases glucose into the bloodstream. It can...