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Effects of specific antibodies and immunocompetent cells on tumor growth in passive transfer experiment
A V Zhigunova1, E G Kravtsov, N V Yashina
1Department of Microbiology and Virology, Russian University of Peoples' Friendship, Moscow, Russia. zhigunova2003@mail.ru
Experiments with passive transfer of immunocompetent cell and serum demonstrated suppression of tumor growth after transfer of splenocytes from animals immunized with Trypanosoma cruzi. The nonspecific constituent of antitumor effect of immunocompetent cells was detected. The previously reported oncoprotective effect of mucins 2 and 3 was not confirmed.
Experiments with passive transfer of immunocompetent cell and serum demonstrated suppression of tumor growth after transfer of splenocytes from animals immunized with Trypanosoma cruzi. The nonspecific constituent of antitumor effect of immunocompetent cells was detected. The previously reported oncoprotective effect of mucins 2 and 3 was not confirmed.
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