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Asymmetric cross-dimerization between methyl methacrylate and substituted alkene by Ru(0)-bicyclononadiene complex
Yuki Hiroi1, Nobuyuki Komine, Sanshiro Komiya
1Department of Applied Chemistry, Graduate School of Engineering, Tokyo University of Agriculture and Technology , 2-24-26 Nakacho, Koganei, Tokyo 184-8588, Japan, and Japan Science and Technology Agency (JST) , ACT-C, 4-1-8 Honcho, Kawaguchi, Saitama 332-0012, Japan.
Abstract:
New Ru(0)-naphthalene complexes containing a bicyclononadiene ligand catalyze the linear cross-dimerization between methyl methacrylate and substituted alkenes by an oxidative coupling mechanism. The chiral (S,S)-2-methylbicyclo[3.3.1]nona-2,6-diene complex (S,S)-1b catalyzes asymmetric linear cross-dimerization between methyl methacrylate and 2,5-dihydrofuran to give the cross-dimer in 74% yield in 80% ee.
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