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Unusual features in four canine meningiomas
S Schöniger1, L Woolford, L Jutras
1Department of Pathology and Pathogen Biology, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK. sandra.schoeniger@vetmed.uni-leipzig.de
Journal of Comparative Pathology
|May 11, 2013
Summary
This study details four unique canine meningiomas, some exhibiting features previously unseen in dogs but known in human meningiomas. These findings enhance our understanding of canine brain tumors and their similarities to human counterparts.
Area of Science:
- Veterinary Neurology
- Comparative Pathology
- Oncology
Background:
- Canine meningiomas are common primary brain tumors in dogs.
- Various histological subtypes of canine meningioma are recognized.
- This study investigates rare presentations of canine meningioma.
Observation:
- Four cases of canine meningioma with unusual histological features were identified.
- Tumors were located intracranially or within the vertebral canal.
- Affected dogs varied in breed, age (7-10 years), and sex.
Findings:
- Two meningiomas showed features of gemistocytic astrocytomas with amyloid deposits.
- One meningioma displayed focal rhabdoid tumor characteristics and amyloid deposits.
- A fourth meningioma, a secretory type, contained amianthoid fibers (collagen deposits).
Implications:
- The observed features in canine meningiomas mirror those found in human meningiomas.
- This comparative pathology deepens the understanding of meningioma development.
- Findings may inform diagnostic criteria and therapeutic strategies for canine meningiomas.
