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Updated: May 11, 2026

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
The role of single-photon emission computed tomography/computed tomography in localizing parathyroid adenoma
Dhruba J Dasgupta1, Shaunak Navalkissoor, Rakesh Ganatra
1Department of Nuclear Medicine, St Thomas' Hospital, Guys and St Thomas' NHS Trust, London, UK. djdhrubs@hotmail.com
Abstract:
With hybrid imaging playing an increasingly important role in nuclear medicine, this article reviews the literature on single-photon emission computed tomography/computed tomography (SPECT/CT) in parathyroid scintigraphy. An understanding of parathyroid and neck anatomy is important for accurate reporting of these scans, as this can have an impact on the surgical approach used. The contribution of SPECT/CT over and above SPECT alone is greatest in terms of localization, particularly for ectopic tumours. There remains controversy on the role of SPECT/CT in eutopic tumours, especially when considering such factors as imaging time and the additional radiation dose.
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