Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 11, 2026

Experimental Model of Ligature-Induced Peri-Implantitis in Mice

Experimental Model of Ligature-Induced Peri-Implantitis in Mice

Published on: May 17, 2024

Utilizing micro-computed tomography to evaluate bone structure surrounding dental implants: a comparison with

Stefan Vandeweghe¹, Paulo G Coelho, Christian Vanhove

¹Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden; Department of Periodontology and Oral Implantology, Dental School, Faculty of Medicine and Health sciences, University of Ghent, Belgium.

Journal of Biomedical Materials Research. Part B, Applied Biomaterials

|May 11, 2013

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Coordinated changes in phloem speed and carbon allocation losses maintain phloem carbon dynamics in wheat leaves during drought.

Plant science : an international journal of experimental plant biology·2026

Same author

Ferroptosis-armed dendritic cell vaccines for glioma immunotherapy.

Nature communications·2026

Same author

Investigating phloem transport dynamics in Arabidopsis through compartmental modelling of positron emission tomography data.

Plant methods·2026

Same author

Assimilation dynamics of xylem-transported CO2 by woody tissue photosynthesis revealed with 11C- and 13C-labelling.

Journal of experimental botany·2026

Same author

Motion study on upright patient positioning in walk-through PET: evaluation in a clinical setting.

EJNMMI physics·2025

Same author

Perihematomal changes in glucose metabolism and cell counts in the rat collagenase model for intracerebral hemorrhage.

Scientific reports·2025

This summary is machine-generated.

Microcomputed tomography (µCT) offers a fast, 3D alternative to traditional histology for evaluating dental implant osseointegration. This study found µCT closely aligns with histomorphometry, suggesting its potential as a valuable tool for assessing bone response around implants.

Area of Science:

Biomaterials Science
Dental Implantology
Histomorphometry

Background:

Histology is the gold standard for evaluating dental implant osseointegration but is destructive and labor-intensive.
Microcomputed tomography (µCT) provides rapid, 3D imaging but requires validation for histomorphometric analysis.

Purpose of the Study:

To compare the accuracy of µCT and histomorphometry in assessing bone response to titanium (Ti) and hydroxyapatite (HA) dental implants.
To validate µCT as a tool for quantitative analysis of bone area (BA) and bone-implant contact (BIC).

Main Methods:

32 Ti and 16 HA implants were placed in rabbits, with samples retrieved at 2 and 4 weeks.
Samples were analyzed using µCT for 3D BA and BIC, followed by traditional histology.
Statistical analysis was performed to compare measurements between the two techniques.

Keywords:

bone-implant contact dental implants histomorphometry micro-CT osseointegration

More Related Videos

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Related Experiment Videos

Last Updated: May 11, 2026

Experimental Model of Ligature-Induced Peri-Implantitis in Mice

Experimental Model of Ligature-Induced Peri-Implantitis in Mice

Published on: May 17, 2024

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Trabecular Bone Microarchitecture Evaluation in an Osteoporosis Mouse Model

Published on: September 8, 2023

Main Results:

µCT and histomorphometry showed comparable results for bone-implant contact (BIC) and bone area (BA) for both Ti and HA implants.
A significant difference was observed only in the 2-week bone area for titanium implants (p = 0.008).
Overall, µCT measurements closely correlated with histomorphometric findings.

Conclusions:

µCT is a reliable and accurate method for evaluating bone structure and osseointegration around dental implants.
µCT should be considered a valuable alternative to histology for quantitative histomorphometric analysis in implant research.
This technique offers a faster, non-destructive approach to assess bone response to different implant materials.