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Juvenile dermatomyositis in pregnancy
Anthony Emeka Madu1, Edwin Omih, Elaine Baguley
1Women and Children Hospital, Hull Royal Infirmary, Anlaby Road, Hull HU3 2JZ, UK.
Case Reports in Obstetrics and Gynecology
|May 11, 2013
Summary
Juvenile dermatomyositis (JDM) in pregnancy requires careful management. Remission before conception improves outcomes, while late-pregnancy flares generally have good fetal prognosis.
Area of Science:
- Rheumatology
- Obstetrics
- Pediatrics
Background:
- Juvenile dermatomyositis (JDM) presents diversely in pregnancy.
- Disease activity significantly impacts maternal and fetal health.
Purpose of the Study:
- To review the literature on juvenile dermatomyositis in pregnancy.
- To present a case of JDM with late-pregnancy exacerbation.
Main Methods:
- Literature review of JDM and pregnancy.
- Case report analysis.
Main Results:
- Optimal outcomes are linked to disease remission prior to pregnancy.
- Early pregnancy flares correlate with poorer outcomes.
- Late pregnancy exacerbations (second/third trimester) show better fetal prognosis.
Conclusions:
- Pregnancy in JDM patients is feasible with disease remission.
- Timing of disease flare influences maternal and fetal outcomes.
- Management should focus on achieving and maintaining remission.
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