Related Experiment Video
Updated: May 11, 2026

Systematic Approach to Identify Novel Antimicrobial and Antibiofilm Molecules from Plants' Extracts and Fractions to Prevent Dental Caries
Published on: March 31, 2021
[Preliminary screen of high cariogenicity Streptococcus mutans strains isolated from clinical specimens]
Chenglong Wang1, Jiaojiao Liu, Donghua Su
1Dept. of Stomatology, Chinese PLA General Hospital, Beijing 100853, China.
Objective:
To screen of high cariogenicity Streptococcus mutans (S. mutans) strains isolated from clinical specimens preliminary.
Methods:
Acidogenicity, aciduricity, extracellular polysaccharide production and adhesion of 41 strains of S. mutans isolated from clinical specimens were investigated to screen high cariogenicity S. mutans strains.
Results:
There were different cariogenicity among 41 strains of S. mutans, in which 3 strains of S. mutans had all high ability to produce extracellular polysaccharide, adhere to the saliva-coated hydroxyapatite, produce acid and tolerate acid, indicated there were 3 strains with high cariogenicity S. mutans strains isolated from clinical specimens. Another 3 strains of S. mutans with all low ability to produce extracellular polysaccharide, adhere to the saliva-coated hydroxyapatite, produce acid and tolerate acid indicated they were low cariogenicity S. mutans strains isolated from clinical specimens.
Conclusion:
We may have obtained high cariogenicity S. mutans strains isolated from clinical specimens.

