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Updated: May 11, 2026

Time-resolved ElectroSpray Ionization Hydrogen-deuterium Exchange Mass Spectrometry for Studying Protein Structure and Dynamics
09:18

Time-resolved ElectroSpray Ionization Hydrogen-deuterium Exchange Mass Spectrometry for Studying Protein Structure and Dynamics

Published on: April 17, 2017

Characterizing rapid, activity-linked conformational transitions in proteins via sub-second hydrogen deuterium

Diana Resetca1, Derek J Wilson

  • 1Department of Chemistry, York University, Toronto, Ontario, Canada.

The FEBS Journal
|May 14, 2013
PubMed

Keywords:
capillary mixerconformational transitionshydrogen/deuterium exchangeintrinsically disordered proteinslabel-free analysismicrofluidicspepsin digestion microreactorprotein dynamicstime-resolved electrospray ionization mass spectrometry‘bottom-up’ HDX workflow

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