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Effects of Taste Signaling Protein Abolishment on Gut Inflammation in an Inflammatory Bowel Disease Mouse Model
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Short-chain fatty acids activate GPR41 and GPR43 on intestinal epithelial cells to promote inflammatory responses in

Myung H Kim1, Seung G Kang, Jeong H Park

  • 1Laboratory of Immunology and Hematopoiesis, Department of Comparative Pathobiology, College of Veterinary Medicine, Purdue University, West Lafayette, Indiana 47907, USA.

Gastroenterology
|May 14, 2013
PubMed
Abstract

Keywords:
2, 4, 6-trinitrobenzene sulfonic-acidATF2C2C3C4CFUColonic InflammationECsERKFITCG-protein−coupled receptorGPRILIntestinal Barrier LeakageKOMAPKMouse ModelPathogenSCFAsT-helper cellTNBSThWTacetateactivating transcription factor 2butyratecolony-forming unitepithelial cellsextracellular signal-regulated kinasefluorescein isothiocyanateinterleukinknock-outmitogen-activated protein kinasepropionateshort-chain fatty acidswild type

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