Precocious puberty as initial presentation in mediastinal tumour
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Manjusha Nair1, P Kusumakumary, Anu Ninan
1Division of Pediatric Oncology, Regional Cancer Centre, Trivandrum, Kerala, India. drmanjushanair@gmail.com
Indian Pediatrics
|May 14, 2013
Abstract:
Numerous disorders can cause precocious puberty in children, and germ cell tumours (GCT) are one of the rare causes . We report two cases of mediastinal malignant GCTs who presented with precocious puberty. Both patients had bulky and advanced disease, were aggressively treated with neo-adjuvant chemotherapy and surgery, and are surviving and free of disease.
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