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Leveraging Turbidity and Thromboelastography for Complementary Clot Characterization
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Dabigatran-associated subdural hemorrhage: using thromboelastography (TEG(®)) to guide decision-making

Ron Neyens1, Nicole Bohm, Madelyne Cearley

  • 1Department of Pharmacy, Medical University of South Carolina, Charleston, SC, USA.

Journal of Thrombosis and Thrombolysis
|May 14, 2013
PubMed

Novel oral anticoagulants present challenges and uncertainties in the management of hemorrhagic emergencies. An 84-year-old man taking dabigatran presented with a subdural hematoma requiring neurosurgical intervention. Routine coagulation assays were prolonged at admission and following administration of Factor VIII Inhibitor Bypassing Activity (FEIBA). Thromboelastography (TEG(®)) was utilized to assess clot dynamics prior to placement of a subdural drain, which was safely inserted despite a prolonged thrombin time (TT). Exclusive reliance on the TT may delay necessary interventions. TEG(®) may be a valuable tool to investigate hemostasis in patients on dabigatran requiring emergent procedures.

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