Potential cause of delayed strokes following carotid artery stenting
Nobuhiko Ogata1, Norihiko Shinozaki, Yuji Ikari
1Department of Cardiovascular Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, Japan, ogatan@is.icc.u-tokai.ac.jp.
Insights
Carotid artery stenting (CAS) is a viable alternative to carotid endarterectomy (CEA). Intravascular ultrasound (IVUS) imaging during CAS may reveal causes of post-procedure stroke.
Area of Science:
- Interventional neurology
- Vascular imaging
- Cerebrovascular disease
Background:
- Carotid artery stenting (CAS) offers an alternative to carotid endarterectomy (CEA) for carotid artery stenosis.
- Randomized trials confirm CAS non-inferiority to CEA regarding major adverse events (MAE).
- A persistent challenge in CAS is the slightly elevated risk of ipsilateral minor stroke post-procedure.
Observation:
- Intravascular ultrasound (IVUS) is routinely used during CAS procedures.
- IVUS imaging provides detailed views of the carotid artery during stenting.
- Specific IVUS findings have been observed in patients experiencing delayed stroke after CAS.
Findings:
- Representative IVUS findings are presented that may explain delayed stroke post-CAS.
- These findings offer insights into the mechanisms of periprocedural stroke.
- The study highlights the potential of IVUS in identifying stroke risks.
Implications:
- Understanding IVUS findings can help mitigate stroke risk associated with CAS.
- This research may lead to improved patient selection and procedural techniques for CAS.
- Further investigation into IVUS markers could enhance the safety of CAS procedures.
Abstract:
Carotid artery stenting (CAS) has been developed as an alternative therapeutic strategy of carotid endarterectomy (CEA) both for symptomatic and asymptomatic extra-cranial carotid artery stenosis. Some randomized clinical trial has been successfully proven the non-inferiority of CAS compared to CEA in terms of efficacy and safety regarding freedom from major adverse event (MAE). One of the remaining problems in CAS is a non-significant but relatively higher incidence of ipsi-lateral minor stroke related to the procedure, both during and soon after the procedure. We routinely examine intravascular ultrasound (IVUS) imaging during the CAS procedure, and found some informative findings. We hereby report the representative IVUS finding, which might suggest the possible cause for delayed stroke after CAS.
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