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Fructose-1,6-diphosphate counteracts ethanol-stimulated calcium uptake in isolated BHK cells
V Rizzoli1, G Battilana, L Galzigna
1Department of Biological Chemistry, University of Padova, Italy.
Molecular and Cellular Biochemistry
|June 1, 1990
Abstract:
Ethanol increases the uptake of 45Ca by isolated baby hamster kidney (BHK) cells in vitro. The effect is dependent on ethanol and 45Ca++ concentration and on the incubation time. Fructose-1,6-diphosphate (FDP) added at different concentration during the pre-incubation exerts a protective effect through a membrane-stabilizing action which is consistent with its in vivo anti-alcohol activity documented in previous studies.