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Electroactive Polymer Nanoparticles Exhibiting Photothermal Properties
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Published on: January 8, 2016

Butyl methoxy dibenzoylmethane.

Jutta Kockler1, Sherryl Robertson, Michael Oelgemöller

  • 1School of Pharmacy and Molecular Science, James Cook University, Townsville, Queensland, Australia.

Profiles of Drug Substances, Excipients, and Related Methodology
|May 15, 2013
PubMed
Summary
This summary is machine-generated.

This profile details Butyl methoxy dibenzoylmethane (Avobenzone), a common UV filter in sunscreens. It covers its properties, analysis, stability, and toxicity, highlighting its UVA I absorbance and photodegradation susceptibility.

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Area of Science:

  • Cosmetic Science
  • Photochemistry
  • Analytical Chemistry

Background:

  • Butyl methoxy dibenzoylmethane, commonly known as Avobenzone, is a widely utilized UV filter in sunscreen formulations.
  • It primarily absorbs UVA I radiation but is prone to photodegradation, impacting its efficacy and stability in products.

Purpose of the Study:

  • To create a comprehensive profile of Butyl methoxy dibenzoylmethane (Avobenzone).
  • To document its general information, usage, preparation, physical characteristics, analytical methods, stability, and toxicity.

Main Methods:

  • Literature review and data compilation on Avobenzone.
  • Analysis of physical characteristics using techniques like DSC, NMR, MS, and X-ray diffractometry.
  • Review of analytical methods including chromatography (TLC, GC, HPLC) and compendial assays.

Main Results:

  • Detailed characterization of Avobenzone's physical and chemical properties.
  • Documentation of various analytical techniques for identification, purity, and assay.
  • Information on Avobenzone's photostability, photostabilization strategies, and toxicological data.

Conclusions:

  • Butyl methoxy dibenzoylmethane (Avobenzone) is a critical UVA filter with well-defined properties and analytical methods.
  • Understanding its photodegradation and stability is essential for effective sunscreen formulation and safety assessment.