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Updated: May 11, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Psoriasis.

Nancy Weigle¹, Sarah McBane

¹Duke University School of Medicine, Durham, NC 27710, USA. nancy.weigle@duke.edu

American Family Physician

|May 15, 2013

Summary

This summary is machine-generated.

Psoriasis is a chronic inflammatory skin disease affecting 2% of U.S. adults, impacting quality of life. Management requires individualized treatment plans combining therapies for optimal outcomes.

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Last Updated: May 11, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

Dermatology
Immunology
Systemic Inflammatory Diseases

Background:

Psoriasis is a chronic inflammatory skin condition with significant quality of life impact.
It affects approximately 2% of the U.S. adult population.
Etiology involves genetic and environmental factors, with plaque psoriasis being the most common form.

Purpose of the Study:

To provide a comprehensive overview of psoriasis, including its various forms and associated systemic conditions.
To discuss diagnostic criteria and current therapeutic strategies for managing psoriasis.
To highlight the importance of individualized treatment approaches for this complex disease.

Main Methods:

Review of current medical literature on psoriasis.
Analysis of diagnostic features and classification of psoriasis subtypes.
Evaluation of treatment modalities, including topical, phototherapy, systemic, and biologic agents.

Main Results:

Psoriasis presents with characteristic skin lesions and can manifest in atypical forms.
Common comorbidities include cardiovascular disease, lymphoma, and depression.
Treatment effectiveness varies by severity, with topical agents for mild cases and systemic/biologic therapies for severe disease.

Conclusions:

Effective psoriasis management necessitates an individualized approach.
Treatment may involve combination therapies, including medications and phototherapy.
Ongoing monitoring is crucial, especially for patients on systemic or biologic treatments due to potential adverse effects.