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Updated: May 11, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Cardiac MRI of acute coronary syndrome
Shamruz Akerem Khan, Shamruz Akarem Khan1, Eric E Williamson
1Department of Radiology, Mayo Clinic, 200 First Street, Southwest Rochester, MN 55905, USA.
Insights
Cardiac MRI aids in diagnosing acute coronary syndrome (ACS) when clinical presentation is unclear. This review details MRI techniques for accurate ACS detection, differential diagnosis, and patient risk stratification.
Area of Science:
- Cardiology
- Medical Imaging
- Diagnostic Medicine
Background:
- Acute coronary syndrome (ACS) presents diagnostic challenges due to varied symptoms and overlap with other chest pain causes.
- While troponin biomarkers have improved ACS diagnosis, clinical uncertainty persists.
- Cardiac MRI is emerging as a valuable tool in managing ACS.
Purpose of the Study:
- To review cardiac MRI techniques for accurate ACS detection and differential diagnosis.
- To highlight MRI's role in guiding clinical decisions and risk stratification post-ACS.
- To present the utility of cardiac MRI in identifying ACS sequelae and prognostication.
Main Methods:
- Review of current literature on cardiac MRI applications in ACS.
- Focus on specific MRI sequences and protocols relevant to ACS diagnosis.
- Analysis of how MRI findings correlate with clinical outcomes and patient management.
Main Results:
- Cardiac MRI offers high accuracy in detecting myocardial injury indicative of ACS.
- MRI effectively differentiates ACS from other causes of chest pain.
- MRI findings provide crucial information for risk stratification and guiding treatment decisions.
Conclusions:
- Cardiac MRI is a powerful imaging modality for the comprehensive evaluation of ACS.
- Integrating cardiac MRI into clinical practice can improve diagnostic accuracy and patient outcomes.
- Further research can refine MRI protocols for even more precise ACS assessment.
Abstract:
Acute coronary syndrome (ACS) is a major cause of morbidity and mortality worldwide. New serological biomarkers, such as troponins, have improved the diagnosis of ACS; however, the diagnosis of ACS can still be difficult as there is marked heterogeneity in its presentation and significant overlap with other disorders presenting with chest pain. Evidence is accumulating that cardiac MRI provides information that can aid the detection and differential diagnosis of ACS, guide clinical decision-making and improve risk-stratification after an event. In this review, we present the relevant cardiac MRI techniques that can be used to detect ACS accurately, provide differential diagnosis, identify the sequelae of ACS, and determine prognostication after ACS.
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