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Published on: May 16, 2025
Laryngeal involvement in rheumatoid arthritis
Sarah Cristina Beirith1, Claudio Marcio Yudi Ikino, Ivânio Alves Pereira
1UFSC, Brazil.
Rheumatoid Arthritis (RA) frequently causes laryngeal issues, with 72.4% of patients showing changes. However, voice disorders (dysphonia) were less common at 12.8% and not linked to disease activity.
Area of Science:
- Otolaryngology
- Rheumatology
- Clinical Medicine
Background:
- Laryngeal involvement in Rheumatoid Arthritis (RA) is common, ranging from 13-75%.
- Manifestations include cricoarytenoid arthritis and vocal fold rheumatoid nodules.
- Understanding these laryngeal effects is crucial for RA patient care.
Purpose of the Study:
- To determine the prevalence of dysphonia and videolaryngoscopy findings in RA patients.
- To investigate the association between laryngeal alterations and RA disease activity.
Main Methods:
- A cross-sectional study compared RA patients with a control group.
- Evaluated disease activity using DAS-28, laryngeal symptoms, Voice Handicap Index, and videolaryngoscopy.
- Assessed 47 RA patients and 40 controls.
Main Results:
- Prevalence of dysphonia was 12.8% and videolaryngoscopy changes was 72.4% in RA patients.
- Posterior laryngitis was the most frequent diagnosis (44.7%).
- No significant association was found between laryngeal disorders and disease activity (p = 0.713).
Conclusions:
- A high prevalence of laryngeal disorders (72.4%) exists in RA patients.
- Dysphonia affects 12.8% of RA patients.
- Laryngeal disorders in RA are not significantly related to disease activity.
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