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Updated: May 11, 2026

An Improved and High Throughput Respiratory Syncytial Virus (RSV) Micro-neutralization Assay
Published on: January 26, 2019
[Vaccine coverage related to lower mortality for respiratory diseases]
Angelo José Gonçalves Bós1, Andrea Ribeiro Mirandola
1Instituto de Geriatria e Gerontologia, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, RS, 90610-000. angelo.bos@pucrs.br
Abstract:
Respiratory infections are a group of diseases commonly related to the elderly, since the influenza virus is one of the main etiological agents. Vaccination of these individuals is considered by the World Health Organization to be the most effective strategy to reduce morbidity and mortality from the disease. Brazil has sought in recent years to vaccinate 80% of the target population. This study sought to relate the vaccination coverage for influenza and the mortality rate from respiratory diseases in the elderly. This was a cross-sectional study with secondary data analysis. Data on vaccination coverage in 2010 of the 496 municipalities of the elderly in Rio Grande do Sul were obtained from the website of the National Immunization Program and mortality in the Mortality Information System. The results showed that 49% of municipalities reached the target of 80% of seniors vaccinated. In municipalities with below target vaccination coverage, the number of deaths was 5.2 per 1,000 elderly. This average is significantly higher than in municipalities with coverage equal to or above 80%. The conclusion is that the target proposed by the Brazilian Ministry of Health to vaccinate 80% or more of the elderly is effective in reducing mortality from respiratory diseases.
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