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Related Experiment Videos

Ascites in growing broilers: a research model.

D A Witzel1, W E Huff, L F Kubena

  • 1USDA/ARS-Veterinary Toxicology and Entomology Research Laboratory, College Station, Texas 77841.

Poultry Science
|May 1, 1990
PubMed
Summary
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High-altitude simulation reliably induced ascites in broiler chickens, impacting their growth and physiology. This model is crucial for understanding the causes of ascites in poultry.

Area of Science:

  • Animal Science
  • Physiology
  • Avian Health

Background:

  • Ascites syndrome is a significant welfare and economic issue in broiler chickens.
  • Environmental factors, such as altitude, are implicated in ascites development.

Purpose of the Study:

  • To develop and validate a high-altitude simulation model for experimentally inducing ascites in broiler chickens.
  • To investigate the physiological and pathological effects of simulated high altitude on broiler chickens.

Main Methods:

  • Broiler chickens were exposed to simulated altitudes (1,980m, 2,438m, 2,896m) in hypobaric chambers for 5 weeks.
  • Control groups were reared under standard conditions.
  • Ascites incidence, body weight, hematological parameters, corticosterone levels, and histopathology were assessed.

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Main Results:

  • Ascites incidence increased with simulated altitude, reaching 80% at 2,896m.
  • Body weight was significantly reduced in high-altitude groups.
  • Hematocrit, hemoglobin, and red blood cell counts increased, while corticosterone levels decreased at higher altitudes.
  • Histopathology revealed cardiopulmonary lesions consistent with spontaneous ascites.

Conclusions:

  • High-altitude simulation is an effective method for producing ascites in broiler chickens.
  • This model provides a valuable tool for studying the etiology and contributing factors of ascites syndrome in poultry.
  • Findings highlight the impact of hypoxia on broiler physiology and health.