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Related Concept Videos

Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
Modified-Release Drug Delivery Systems: Overview01:19

Modified-Release Drug Delivery Systems: Overview

Modified-release dosage forms are designed to address the limitations of drugs with short biological half-lives. These forms maintain stable therapeutic drug concentrations over extended periods, reducing the need for frequent dosing. A consistent drug level helps minimize peak-trough fluctuations, which can reduce adverse effects, lower the risk of drug resistance, and improve overall treatment effectiveness.One common type of modified-release form is the extended-release (ER) formulation. ER...
Oral Drug Delivery Systems: Introduction01:23

Oral Drug Delivery Systems: Introduction

Oral drug delivery is the most common route of administration due to its convenience, cost-effectiveness, and high patient compliance. It enables precise formulation to ensure proper drug dosage and bioavailability. The development of oral dosage forms considers drug properties such as solubility, stability, and absorption to optimize therapeutic efficacy.Tablets, capsules, liquids, and chewable formulations enhance drug stability, mask undesirable tastes, and improve patient experience.
Drug Delivery: Overview01:16

Drug Delivery: Overview

The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the gastrointestinal...
Drug Delivery Systems: Different Types01:27

Drug Delivery Systems: Different Types

Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
Modified-Release Drug Delivery Systems: Classification01:23

Modified-Release Drug Delivery Systems: Classification

Modified-release drug delivery systems improve drug efficacy and minimize side effects by controlling the rate and location of drug release. These systems fall into three categories: rate-programmed, stimuli-activated, and site-targeted.Rate-programmed systems release drugs at a predetermined rate, maintaining consistent therapeutic levels and reducing fluctuations that could lead to toxicity or subtherapeutic effects. These systems use polymeric matrices, reservoir-based designs, or osmotic...

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Related Experiment Video

Updated: May 11, 2026

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
09:39

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications

Published on: February 7, 2021

Cyclodextrin-based supramolecular systems for drug delivery: recent progress and future perspective.

Jianxiang Zhang1, Peter X Ma

  • 1Department of Pharmaceutics, College of Pharmacy, Third Military Medical University, Chongqing 400038, China.

Advanced Drug Delivery Reviews
|May 16, 2013
PubMed
Summary
This summary is machine-generated.

Cyclodextrins are versatile materials for creating advanced drug delivery systems. This review highlights their use in supramolecular assemblies like nanoplatforms and hydrogels for improved biomedical applications.

Keywords:
AmphiphileCyclodextrinDrug deliveryGene therapyHydrogelNanomedicineNanoparticleSelf-assemblySupramolecular system

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Last Updated: May 11, 2026

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
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An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart
10:28

An Injectable and Drug-loaded Supramolecular Hydrogel for Local Catheter Injection into the Pig Heart

Published on: June 7, 2015

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Supramolecular Chemistry

Background:

  • Cyclodextrins (CDs) and their derivatives offer excellent biocompatibility, inclusion capabilities, and functionalization potential.
  • There is growing interest in using CD-based supramolecular systems for advanced drug and gene delivery applications.

Purpose of the Study:

  • To review the state-of-the-art and recent advancements in constructing cyclodextrin-based assemblies.
  • To highlight the applications of these supramolecular systems in controlled drug delivery, nanomedicine, and pharmaceutical sciences.

Main Methods:

  • Introduction of cyclodextrin materials suitable for self-assembly.
  • Discussion of fabrication technologies for supramolecular systems, including nanoplatforms and hydrogels.

Main Results:

  • Cyclodextrin-based assemblies demonstrate significant potential for controlled drug delivery.
  • These materials are effectively utilized in nanomedicine and pharmaceutical sciences.

Conclusions:

  • Cyclodextrin-based supramolecular systems represent a promising frontier in developing novel functional materials for biomedical applications.
  • Future research directions in this field are crucial for further innovation.