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Related Concept Videos

Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Classes and Categories01:25

Drug Classes and Categories

Drugs can be classified according to their chemical composition or their intended therapeutic application. For instance, anti-infective agents that possess the ability to eliminate pathogens or suppress their growth and reproduction can be grouped based on the organisms they target or their chemical structure. Furthermore, drugs can be divided into prescription, nonprescription, or controlled substances. Prescription medications, such as antibiotics, require oversight from a licensed healthcare...
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
Dosage Regimens: Partial Pharmacokinetic Parameters01:01

Dosage Regimens: Partial Pharmacokinetic Parameters

It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
Pharmacogenetics and Pharmacogenomics: Overview01:29

Pharmacogenetics and Pharmacogenomics: Overview

Pharmacogenetics and pharmacogenomics examine how genetic factors influence an individual's response to drugs. While pharmacogenetics focuses on the impact of specific genetic variants on drug effects, pharmacogenomics takes a broader approach, studying how genetic variation across populations contributes to differences in drug responses. These fields aim to explain why individuals may experience varying levels of efficacy or adverse reactions to the same medication.Variability in drug...

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Related Experiment Video

Updated: May 11, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Do general practitioners know what they are prescribing?

Ali Jawaid1, Dileep Kumar Rohra, Abdul Mueed Zafar

  • 1Institute of Neuropathology, University Hospital Zurich, Switzerland.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|May 16, 2013
PubMed
Summary

General practitioners (GPs) showed limited knowledge of drug adverse effects, particularly those relying on pharmaceutical ads. Experience level and information source significantly impacted GP knowledge on drug use and side effects.

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Last Updated: May 11, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
11:39

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Area of Science:

  • Pharmacology
  • General Practice
  • Medical Education

Background:

  • General practitioners (GPs) play a crucial role in medication management.
  • Accurate knowledge of therapeutic uses and adverse effects is essential for safe prescribing.
  • Understanding GPs' knowledge gaps is vital for improving drug safety and patient outcomes.

Purpose of the Study:

  • To assess general practitioners' knowledge of the therapeutic uses and adverse effects of commonly prescribed medications.
  • To identify factors influencing GPs' knowledge, such as information sources and experience.

Main Methods:

  • A cross-sectional study involving 131 general practitioners in Pakistan.
  • Assessment of knowledge on three specific drugs: Montelukast Sodium, Somatriptan, and Fluticasone Propionate.
  • A questionnaire-based approach with multiple-choice questions on drug cost, therapeutic use, and adverse effects.

Main Results:

  • 61.2% of GPs correctly identified the therapeutic uses of the selected drugs.
  • Only 40.8% of GPs correctly identified common adverse effects.
  • A significant knowledge deficit in adverse effects was linked to reliance on pharmaceutical advertisements and lower GP experience (p < 0.01).

Conclusions:

  • General practitioners demonstrate adequate knowledge of drug therapeutic uses but significant gaps in understanding adverse effects.
  • Information sources, particularly pharmaceutical advertisements, and professional experience level are critical factors influencing GPs' drug knowledge.
  • Targeted educational interventions are needed to enhance GPs' understanding of medication adverse effects and improve prescribing practices.