Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Structural Joints: Synovial Joints01:16

Structural Joints: Synovial Joints

Synovial joints are the most common type of joint in the body. A key structural characteristic for a synovial joint is the presence of a joint cavity. This fluid-filled space is where the articulating surfaces of the bones contact each other. Also, unlike fibrous or cartilaginous joints, the articulating bone surfaces at a synovial joint are not directly connected to each other with fibrous connective tissue or cartilage. This gives the bones of a synovial joint the ability to move smoothly...
Development of the Limb Synovial Joints01:07

Development of the Limb Synovial Joints

Joints form during embryonic development in conjunction with the formation and growth of the associated bones. The embryonic tissue that gives rise to all bones, cartilage, and connective tissues of the body is called mesenchyme.
The mesenchymal stem cells differentiate into chondrocytes that form the hyaline cartilage, and later the cartilaginous model of the bone. This model further transforms into a bone. This process is known as endochondral ossification.
During development, the limbs...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Artificial Intelligence Applications in Degenerative Musculoskeletal Diseases.

Magnetic resonance imaging clinics of North America·2026
Same author

Optimizing Radiography Utilization: Multidisciplinary Expert Consensus Recommendations Endorsed by the Society of Academic Bone Radiologists, Society of Skeletal Radiology, American Society of Emergency Radiology, Orthopaedic Trauma Association, American Academy of Emergency Medicine, and American Rhinologic Society.

Radiology·2026
Same author

Non-Typhoidal <i>Salmonella enterica</i> Bacteremia Complicated by Native Shoulder Septic Arthritis in a Patient with Sickle Cell Disease Following Foodborne Exposure: A Case Report and Literature Review.

Infectious disease reports·2026
Same author

RADS classification systems for bone tumors: current status and where do we go from here?

Cancer imaging : the official publication of the International Cancer Imaging Society·2026
Same author

Soft tissue reporting and data system (soft tissue-RADS): framework for radiologists specializing in imaging of musculoskeletal tumors and tumor-like lesions.

Skeletal radiology·2026
Same author

Granular Machine Learning-Based Computed Tomography Contrast Phase Prediction.

Mayo Clinic proceedings. Digital health·2026

Related Experiment Video

Updated: May 11, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Benign synovial tumors and proliferative processes.

Hillary W Garner1, Joseph M Bestic

  • 1Department of Radiology, Mayo Clinic Florida, Jacksonville, FL 32224, USA. garner.hillary@mayo.edu

Seminars in Musculoskeletal Radiology
|May 16, 2013
PubMed
Summary

This review covers benign synovial tumors like giant cell tumors and lipomas. It highlights key imaging features for accurate diagnosis of these common joint conditions.

Area of Science:

  • Orthopedic Pathology
  • Radiology
  • Musculoskeletal Imaging

Background:

  • The synovium can develop various benign tumors and proliferative conditions.
  • Accurate differentiation of these entities is crucial for appropriate patient management.
  • Imaging plays a pivotal role in diagnosing synovial lesions.

Purpose of the Study:

  • To review the clinical and imaging features of common benign synovial tumors and proliferative processes.
  • To emphasize characteristic imaging findings that aid in diagnosis.
  • To provide a guide for differentiating these entities on medical imaging.

Main Methods:

  • Literature review of benign synovial tumors and proliferative processes.
  • Analysis of clinical presentations and characteristic imaging findings (MRI, CT, Ultrasound).

Related Experiment Videos

Last Updated: May 11, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

  • Correlation of imaging features with histopathological diagnoses.
  • Main Results:

    • Giant cell tumor of the tendon sheath, pigmented villonodular synovitis, and synovial chondromatosis exhibit distinct imaging patterns.
    • Lipoma arborescens, synovial hemangioma, lipoma, and fibroma also have recognizable imaging characteristics.
    • Specific imaging findings can significantly narrow the differential diagnosis for synovial lesions.

    Conclusions:

    • Benign synovial tumors and proliferative processes have diverse clinical and imaging manifestations.
    • Radiologists can often confidently diagnose or limit the differential diagnosis of these conditions based on imaging.
    • Understanding these imaging features is essential for effective orthopedic and rheumatologic patient care.