[Interleukin 1 secretion from alveolar macrophages in pulmonary sarcoidosis]

Alveolar macrophages obtained from 28 patients with pulmonary sarcoidosis were investigated to determine their ability spontaneously to release interleukin 1. In 14 of these patients, a significant spontaneous liberation of interleukin 1 was observed; the BAL parameters of these patients pointed to an elevated activity of the disease.