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Updated: May 11, 2026

In Vivo, Percutaneous, Needle Based, Optical Coherence Tomography of Renal Masses
Published on: March 30, 2015
Perirenal fat invasion on renal cell carcinoma: evaluation with multidetector computed tomography-multivariate
Athina C Tsili1, Anna C Goussia, Dimitrios Baltogiannis
1Departments of Clinical Radiology, University Hospital of Ioannina, Ioannina, Greece. a_tsili@yahoo.gr
Objective:
The objective of this study was to assess the accuracy of multidetector computed tomography (CT) in diagnosing perinephric (PN) and/or renal sinus (RS) fat invasion in patients with renal cell carcinoma (RCC), with reference to the CT findings predictive for the diagnosis of invasion.
Methods:
This was a retrospective study of 48 RCCs. Examinations were performed on a 16-row CT scanner, including unenhanced and 3-phase contrast-enhanced CT scanning. Unenhanced transverse images and multiplanar reformations of each contrast-enhanced CT phase were evaluated. The predictive value of CT findings in diagnosing PN and/or RS fat invasion was determined using multivariate logistic regression analysis.
Results:
The CT findings that were most predictive for the diagnosis of PN fat invasion were the presence of contrast-enhancing nodules in the PN fat and tumoral margins. Invasion of the pelvicaliceal system was the most significant predictor in the diagnosis of RS fat invasion.
Conclusions:
Multidetector CT provides satisfactory results in detecting PN and/or RS fat invasion in RCC.
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