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The relationship between osteoarthritis and cardiovascular disease in a population health survey: a cross-sectional

M Mushfiqur Rahman1, Jacek A Kopec, Jolanda Cibere

  • 1School of Population and Public Health, University of British Columbia Vancouver, British Columbia, Canada.

BMJ Open
|May 16, 2013
PubMed

Insights

Osteoarthritis (OA) is linked to a higher risk of heart disease, including angina and congestive heart failure (CHF), in both men and women. This finding highlights the importance of considering cardiovascular health in OA patients.

Area of Science:

  • Cardiovascular Health
  • Rheumatology
  • Public Health

Background:

  • Osteoarthritis (OA) is a prevalent degenerative joint disease.
  • Heart diseases, including myocardial infarction (MI), angina, congestive heart failure (CHF), and stroke, are leading causes of morbidity and mortality.
  • The relationship between OA and cardiovascular diseases requires further elucidation.

Purpose of the Study:

  • To investigate the association between osteoarthritis and the prevalence of heart diseases and stroke.
  • To determine if this association differs between men and women.

Main Methods:

  • A cross-sectional study utilizing data from the Canadian Community Health Survey (CCHS) cycles 1.1, 2.1, and 3.1.
  • Inclusion of 40,817 self-reported OA cases and 1:1 matched non-OA controls.
  • Multivariable logistic regression models were employed to analyze the association, adjusting for various sociodemographic and health-related factors.

Main Results:

  • Osteoarthritis was associated with an increased odds of prevalent heart disease (OR 1.45).
  • Specific associations were observed for angina and CHF in both sexes, and for MI in women.
  • Adjusted odds ratios indicated a significant link between OA and angina (ORs ranging from 1.76 to 1.84) and CHF (ORs ranging from 1.50 to 1.81).

Conclusions:

  • Prevalent osteoarthritis is significantly associated with self-reported heart disease, particularly angina and CHF, in both men and women.
  • These findings persist after controlling for established cardiovascular risk factors.
  • Further longitudinal research is warranted to explore potential biological and behavioral mechanisms underlying the OA-heart disease connection.
Abstract

Keywords:
Epidemiology

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