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An Immunological Model for Heterotopic Heart and Cardiac Muscle Cell Transplantation in Rats
Published on: May 8, 2020
Troubling dimensions of heart transplantation
M Shildrick1, P McKeever, S Abbey
1School of Sociology, Social Policy and Social Work, Queens University Belfast, Belfast, UK.
Insights
Heart transplant recipients may experience unexpected distress due to the profound bodily and identity changes from receiving another person's heart. A phenomenological approach can improve patient care and understanding of these experiences.
Area of Science:
- Psychology
- Philosophy
- Medical Ethics
Background:
- Heart transplantation is a standard treatment for end-stage heart failure.
- Current approaches view the transplanted heart mechanistically, overlooking psychosocial impacts.
- Recipients sometimes report unexplained distress post-transplant.
Purpose of the Study:
- To explore the psychosocial and identity implications of heart transplantation.
- To propose phenomenology as a framework for understanding recipient experiences.
- To suggest improvements in patient care based on a holistic understanding.
Main Methods:
- The study frames an ongoing empirical investigation using phenomenological philosophy.
- It draws on theories of embodiment and selfhood (e.g., Merleau-Ponty).
- It analyzes recipient reflections on incorporating a donor heart.
Main Results:
- Biomedical models alone are insufficient to explain post-transplant psychosocial distress.
- Changes to the body, specifically the heart, can profoundly transform the self.
- Phenomenological insights can illuminate previously inexplicable adverse outcomes.
Conclusions:
- Heart transplantation involves more than a technical procedure; it impacts embodiment and identity.
- Acknowledging these disturbances can improve understanding of patient outcomes.
- A phenomenological perspective can enhance consent, preoperative education, and follow-up care.
Abstract:
Heart transplantation is now the accepted therapy for end-stage heart failure that is resistant to medical treatment. Families of deceased donors routinely are urged to view the heart as a "gift of life" that will enable the donor to live on by extending and sustaining the life of a stranger. In contrast, heart recipients are encouraged to view the organ mechanistically-as a new pump that was rendered a spare, reusable part when a generous stranger died. Psychosocial and psychoanalytic research, anecdotal evidence and first-person accounts indicate that after transplant, many recipients experience unexpected changes or distress that cannot be understood adequately using biomedical explanatory models alone. In this paper it is argued that phenomenological philosophy offers a promising way to frame an ongoing empirical study that asks recipients to reflect on what it is like to incorporate the heart of another person. Merleau-Ponty and others have posited that any change to the body inevitably transforms the self. Hence, it is argued in this paper that replacing failing hearts with functioning hearts from deceased persons must be considered much more than a complex technical procedure. Acknowledging the disturbances to embodiment and personal identity associated with transplantation may explain adverse outcomes that heretofore have been inexplicable. Ultimately, a phenomenological understanding could lead to improvements in the consent process, preoperative teaching and follow-up care.
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