Related Experiment Videos
[IgG subclass distribution in the serum of patients with homozygous alpha1-antitrypsin deficiency]
J Barth1, I Winkler, E W Schmidt
1Medizinische Klinik Bergmannsheil, Ruhr-Universität, Bochum.
Pneumologie (Stuttgart, Germany)
|February 1, 1990
Abstract:
In 12 patients with homozygotic ZZ-phenotype alpha 1 antitrypsin deficiency, the serum levels of the IgG subclasses IgG1-4 were studied. In four of these patients, isolated or combined disorders or defects in the distribution of the IgG subclasses were detected; in cases with low IgG2 and absent IgG3, the clinical course of the disease was complicated by bronchiectasis.