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Related Experiment Video

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Procedure and Key Optimization Strategies for an Automated Capillary Electrophoretic-based Immunoassay Method

Procedure and Key Optimization Strategies for an Automated Capillary Electrophoretic-based Immunoassay Method

Published on: September 10, 2017

Immunoassay Methods and their Applications in Pharmaceutical Analysis: Basic Methodology and Recent Advances.

Ibrahim A Darwish¹

¹Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Egypt.

International Journal of Biomedical Science : IJBS

|May 16, 2013

Summary

Immunoassays, crucial for pharmaceutical analysis, utilize antigen-antibody reactions for precise analyte quantification. Recent advancements enhance their specificity, sensitivity, and throughput for drug discovery and diagnostics.

Keywords:

antibodies drug discovery immunoassay pharmaceutical analysis pharmaceutical industry

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Area of Science:

Analytical Chemistry
Biochemistry
Pharmaceutical Sciences

Background:

Immunoassays are vital bioanalytical techniques quantifying analytes via antigen-antibody reactions.
They are extensively used in pharmaceutical analysis, including disease diagnosis, therapeutic drug monitoring, and pharmacokinetic studies.

Purpose of the Study:

To review the fundamental methodologies of immunoassays.
To highlight recent advancements in immunoassay development for pharmaceutical analysis.

Main Methods:

Review of established immunoassay principles.
Analysis of recent innovations in reagent preparation, compound analysis, and instrumentation.

Main Results:

Immunoassays offer high specificity, throughput, and sensitivity for analyzing diverse analytes in biological samples.
Recent improvements focus on novel reagents, new compound categories, and advanced methodologies and instrumentation.

Conclusions:

Immunoassays remain indispensable tools in pharmaceutical analysis due to their performance characteristics.
Ongoing developments continue to expand their utility and effectiveness in drug discovery and related fields.