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Related Concept Videos

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Chronic Kidney Disease II: Clinical Manifestations

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Related Experiment Videos

Idiopathic Benign Hyper-CK-Emia.

Prashant Kaushik1, Anuradha Gonuguntla

  • 1Specialty Clinics, St. Alexius Medical Center, Bismarck, North Dakota, USA;

International Journal of Biomedical Science : IJBS
|May 16, 2013
PubMed
Summary
This summary is machine-generated.

Idiopathic benign hyper-CK-emia, a condition of elevated serum creatine (phospho) kinase, is often overlooked by primary care physicians. This study highlights its benign nature in 16 adult patients, emphasizing the need for better recognition.

Keywords:
benignhyper-CK-emiaidiopathic

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Area of Science:

  • Rheumatology
  • Clinical Medicine
  • Biochemistry

Background:

  • Persistent elevation of serum creatine (phospho) kinase (CK) levels, or hyper-CK-emia, frequently prompts rheumatology consultation.
  • Idiopathic benign hyper-CK-emia is a recognized condition in medical literature but often underdiagnosed by primary care physicians.
  • Early recognition is crucial for differentiating benign cases from more serious myopathies.

Observation:

  • A descriptive analysis of 16 consecutive adult patients with idiopathic benign hyper-CK-emia was conducted.
  • Patients were evaluated at a tertiary care Rheumatology Clinic in Bismarck, North Dakota.
  • The study observed the clinical course and laboratory findings associated with this condition.

Findings:

  • The study identified idiopathic benign hyper-CK-emia in 16 adult patients.
  • The condition was characterized by persistent elevation of serum CK levels without an identifiable underlying cause.
  • The observed course of the condition in these patients was benign.

Implications:

  • Increased awareness among primary care physicians regarding idiopathic benign hyper-CK-emia is warranted.
  • This condition's benign nature necessitates distinguishing it from potentially serious neuromuscular disorders.
  • This report represents the first documentation of idiopathic benign hyper-CK-emia in North Dakota, contributing to broader medical literature.