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Updated: May 11, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Practical pearls in phototherapy.

Cindy L Tsui1, Jacob Levitt

  • 1New York University, New York, NY, USA; The Mount Sinai School of Medicine, New York, NY, USA.

International Journal of Dermatology
|May 17, 2013
PubMed
Summary
This summary is machine-generated.

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Phototherapy requires regular calibration and bulb replacement for optimal function. Proper dosing and management of side effects like burns and nausea are crucial for effective ultraviolet (UV) and psoralen-plus-ultraviolet-A (PUVA) treatments.

Area of Science:

  • Dermatology
  • Photobiology

Background:

  • Phototherapy, including ultraviolet B (UVB) and psoralen-plus-ultraviolet-A (PUVA), is a common dermatological treatment.
  • Effective and safe application requires adherence to specific protocols.

Purpose of the Study:

  • To provide practical guidelines for the optimal use of phototherapy.
  • To detail maintenance, dosing, and side effect management for phototherapy treatments.

Main Methods:

  • The study outlines maintenance schedules for phototherapy units, including calibration and bulb replacement.
  • It details strategies for managing treatment-induced erythema (burns) and nausea associated with oral psoralens.
  • Specific protocols for preparing hand/foot and full-body soak PUVA solutions are provided.

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Last Updated: May 11, 2026

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Main Results:

  • Regular calibration (every 2-4 weeks) and timely bulb replacement (8-10 months or 3-4 mW/cm(2)) ensure unit efficacy.
  • Avoiding consecutive treatment days and reducing doses by 50% aids in managing burns.
  • Nausea can be mitigated through food intake, antiemetics, ginger, or divided dosing.
  • Precise concentrations for hand/foot (0.03%) and full-body (0.000075%) soak PUVA are defined.

Conclusions:

  • Adherence to these phototherapy guidelines can optimize treatment outcomes.
  • Proper equipment maintenance and proactive management of side effects are essential for patient safety and treatment success.