Pemberton lecture. Degradative enzymes in osteoarthritic human articular cartilage

Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization.

Osteoarthritis and cartilage·2001

Basic calcium phosphate crystals up-regulate metalloproteinases but down-regulate tissue inhibitor of metalloproteinase-1 and -2 in human fibroblasts.

Osteoarthritis and cartilage·2001

Effect of 1alpha,25-dihydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3 on metalloproteinase activity and cell maturation in growth plate cartilage in vivo.

Endocrine·2001

Wild type and mutant p53 differentially regulate the gene expression of human collagenase-3 (hMMP-13).

The Journal of biological chemistry·2001

Perturbations in factors that modulate osteoblast functions in vitamin B6 deficiency.

Canadian journal of physiology and pharmacology·2000

Loss of decorin from the surface zone of articular cartilage in a chick model of osteoarthritis.

Acta histochemica·1998

Regional distribution of adult rheumatologists.

Arthritis and rheumatism·2013

Clinically significant renal involvement in primary Sjögren's syndrome: clinical presentation and outcome.

Arthritis and rheumatism·2013

Headache in systemic lupus erythematosus: results from a prospective, international inception cohort study.

Arthritis and rheumatism·2013

Association of low baseline levels of erythrocyte folate with treatment nonresponse at three months in rheumatoid arthritis patients receiving methotrexate.

Arthritis and rheumatism·2013

2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative.

Arthritis and rheumatism·2013

Most patients with cancer-associated dermatomyositis have antibodies to nuclear matrix protein NXP-2 or transcription intermediary factor 1γ.

Arthritis and rheumatism·2013

Non-coding RNAs as regulators of chromosomal instability in breast cancer.

Frontiers in oncology·2026

C-X-C motif chemokine ligand 13 and the C-X-C motif chemokine receptor 5-c-Jun N-terminal kinase-nuclear factor kappa B-matrix metalloproteinase 9 axis in oral squamous cell carcinoma metastasis.

Journal of dental sciences·2026

Resistance-oriented immunometabolic circuits in laryngeal squamous cell carcinoma: glycolysis-lactate signaling, mitochondrial stress, and tumor-myeloid crosstalk.

Frontiers in immunology·2026

A highly potent compound W-1-32 targeting XIAP protein inhibits proliferation and metastasis of esophageal squamous cell carcinoma.

Frontiers in pharmacology·2026

IBD-related inflammatory memory and colorectal cancer: epigenetic mechanisms and microbiome interventions.

Frontiers in immunology·2026

Functions of TIAM1 at the interface of centriole assembly and autolysosome cycling.

bioRxiv : the preprint server for biology·2026

Related Experiment Videos

Pemberton lecture. Degradative enzymes in osteoarthritic human articular cartilage

Related Concept Videos

Altered mechanics and histomorphometry of canine tibial cartilage following joint immobilization.

Basic calcium phosphate crystals up-regulate metalloproteinases but down-regulate tissue inhibitor of metalloproteinase-1 and -2 in human fibroblasts.

Effect of 1alpha,25-dihydroxyvitamin D3 and 24R,25-dihydroxyvitamin D3 on metalloproteinase activity and cell maturation in growth plate cartilage in vivo.

Wild type and mutant p53 differentially regulate the gene expression of human collagenase-3 (hMMP-13).

Perturbations in factors that modulate osteoblast functions in vitamin B6 deficiency.

Loss of decorin from the surface zone of articular cartilage in a chick model of osteoarthritis.

Regional distribution of adult rheumatologists.

Clinically significant renal involvement in primary Sjögren's syndrome: clinical presentation and outcome.

Headache in systemic lupus erythematosus: results from a prospective, international inception cohort study.

Association of low baseline levels of erythrocyte folate with treatment nonresponse at three months in rheumatoid arthritis patients receiving methotrexate.

2013 classification criteria for systemic sclerosis: an American College of Rheumatology/European League against Rheumatism collaborative initiative.

Most patients with cancer-associated dermatomyositis have antibodies to nuclear matrix protein NXP-2 or transcription intermediary factor 1γ.

Non-coding RNAs as regulators of chromosomal instability in breast cancer.

C-X-C motif chemokine ligand 13 and the C-X-C motif chemokine receptor 5-c-Jun N-terminal kinase-nuclear factor kappa B-matrix metalloproteinase 9 axis in oral squamous cell carcinoma metastasis.

Resistance-oriented immunometabolic circuits in laryngeal squamous cell carcinoma: glycolysis-lactate signaling, mitochondrial stress, and tumor-myeloid crosstalk.

A highly potent compound W-1-32 targeting XIAP protein inhibits proliferation and metastasis of esophageal squamous cell carcinoma.

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Pemberton lecture. Degradative enzymes in osteoarthritic human articular cartilage

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