Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Intestinal Obstruction II: Pathophysiology

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...

Inflammatory Bowel Disease II: Crohn's Disease

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...

Endoscopic Procedures II: Colonoscopy

Endoscopic Procedures II: Colonoscopy

The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:

Appendicitis-I: Introduction

Appendicitis-I: Introduction

The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...

Assessment of the Rectum and Anus

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...

Inflammatory Bowel Disease I: Ulcerative Colitis

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Non-operative treatment strategy versus surgery for children with simple appendicitis: non-inferiority randomised controlled trial.

BMJ medicine·2026

Same author

Small Bites vs Large Bites for Closure of Abdominal Midline Incisions: A Randomized Clinical Trial.

JAMA surgery·2026

Same author

Classification of trauma-related preventable death; protocol of a Delphi procedure.

PloS one·2024

Same author

Enhanced Th17 responses in the appendix of children with complex compared to simple appendicitis are associated with microbial dysbiosis.

Frontiers in immunology·2024

Same author

Oral ω-3 PUFA supplementation modulates inflammation in adipose tissue depots in morbidly obese women: A randomized trial.

Nutrition (Burbank, Los Angeles County, Calif.)·2023

Same author

Using Existing Clinical Information Models for Dutch Quality Registries to Reuse Data and Follow COUMT Paradigm.

Applied clinical informatics·2023

Search research articles

Related Experiment Video

Updated: May 11, 2026

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Published on: July 12, 2018

[Severe abdominal pain after colostomy].

Annelieke M K Harmsen¹, Mark Tenhagen, Huib A Cense

¹Rode Kruis Ziekenhuis, afd. Heelkunde, Beverwijk, the Netherlands.

Nederlands Tijdschrift Voor Geneeskunde

|May 17, 2013

Summary

A rare internal herniation caused a closed-loop bowel obstruction in a patient with a colostomy. Prompt surgical intervention revealed and repaired an ischemic small bowel segment, preventing further complications.

Area of Science:

Gastroenterology
Surgical Pathology
Abdominal Imaging

Background:

Internal herniation is an uncommon cause of small bowel obstruction.
Patients with prior abdominal surgery, such as colostomy, may be at increased risk.
Early diagnosis and management are critical due to high mortality rates.

Observation:

A 57-year-old male with a history of laparoscopic loop colostomy presented with acute abdominal pain.
Abdominal CT scan revealed a closed-loop bowel obstruction.
Exploratory laparotomy identified an ischemic small bowel segment herniating through a mesocolic defect.

Findings:

Successful repositioning of the herniated small bowel segment.
The compromised bowel segment was noted to be viable after repositioning.

Related Experiment Videos

Last Updated: May 11, 2026

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Murine Distal Colostomy, A Novel Model of Diversion Colitis in C57BL/6 Mice

Published on: July 12, 2018

Mesocolic defect identified as the cause of internal herniation.

Implications:

Highlights the importance of considering internal herniation in patients with prior abdominal surgery presenting with obstruction.
Underscores the critical role of prompt diagnosis and surgical intervention in managing internal herniation.
Emphasizes the potential for bowel ischemia and strangulation in internal herniation, necessitating urgent surgical repair.