Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Serum osteocalcin and bone turnover in hyperthyroidism].

M León Sanz1, F Hawkins, L Larrodera

  • 1S. Endocrinología y Nutrición, Hospital 12 de Octubre, Madrid.

Revista Clinica Espanola
|March 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immune checkpoint inhibitors use in lung transplant recipients: a case series and systematic review of literature.

ESMO open·2025
Same author

Fungal Planet description sheets: 1614-1696.

Fungal systematics and evolution·2024
Same author

Correction: Emerging pollutants in the Esmeraldas watershed in Ecuador: discharge and attenuation of emerging organic pollutants along the San Pedro-Guayllabamba-Esmeraldas rivers.

Environmental science. Processes & impacts·2024
Same author

[Contraindications to lung transplantation].

Revue des maladies respiratoires·2023
Same author

Forecasting brain activity based on models of spatiotemporal brain dynamics: A comparison of graph neural network architectures.

Network neuroscience (Cambridge, Mass.)·2023
Same author

[Updated indications and contraindications in 2022 for lung transplantation in France].

Revue des maladies respiratoires·2022
Same journal

Vaccination status of patients undergoing HIV treatment in a hospital in Madrid.

Revista clinica espanola·2026
Same journal

Sulfonylureas and fracture risk in patients with type 2 diabetes mellitus: a systematic review and meta-analysis.

Revista clinica espanola·2026
Same journal

Risk factors for the development of in-hospital complications in pluripathological patients.

Revista clinica espanola·2026
Same journal

Features, treatment and 1-year prognosis of patients with heart failure and chronic kidney disease stages 4 or 5.

Revista clinica espanola·2026
Same journal

Notification of suspected adverse drug reactions by nurses to a hospital pharmacovigilance program. Retrospective descriptive study.

Revista clinica espanola·2026
Same journal

Venous thromboembolic disease associated with hormonal contraceptives. Venous Thromboembolism Group of the Spanish Society of Internal Medicine and the Catalan Society of Contraception.

Revista clinica espanola·2026
See all related articles

Hyperthyroidism increases bone turnover, primarily through higher bone resorption. Serum Osteocalcin (BGP), a bone turnover marker, was significantly elevated in hyperthyroid patients, suggesting a complex bone metabolism response.

Area of Science:

  • Endocrinology
  • Bone Metabolism

Context:

  • Hyperthyroidism is associated with increased bone turnover, potentially leading to bone loss.
  • Osteocalcin (BGP) is a specific marker synthesized by osteoblasts, reflecting bone formation and turnover.

Purpose:

  • To evaluate bone turnover complications in hyperthyroidism by measuring serum Osteocalcin (BGP) levels.
  • To assess the relationship between BGP levels and thyroid hormone status in hyperthyroid patients.

Summary:

  • Serum Osteocalcin (BGP) levels were significantly higher in 41 hyperthyroid patients (6.2 +/- 4.2 ng/ml) compared to normal controls (3.7 +/- 1.3 ng/ml).
  • Patients were divided into two groups based on BGP levels, with no significant differences in thyroid hormones or mineral metabolism between groups.
  • Serum BGP and T3 levels showed a correlation, suggesting a link between thyroid hormone levels and bone metabolism markers.

Related Experiment Videos

Impact:

  • The findings suggest a dual effect of hyperthyroidism on bone, impacting both resorption and potentially formation.
  • Results indicate a temporal dissociation between thyroid hormone synthesis and bone metabolism regulation.
  • This study highlights Osteocalcin (BGP) as a valuable marker for assessing bone turnover in hyperthyroidism.