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[Priapism associated with risperidone use: Report of one case]
Lizardo Cruzado1, César E Vallejos
1Instituto Nacional de Salud Mental Honorio Delgado-Hideyo Noguchi, Perú. lizardo_cruzado@yahoo.com
Revista Medica De Chile
|May 17, 2013
Summary
Priapism, a prolonged erection, can be caused by alpha-adrenergic antagonist drugs. A patient treated with risperidone for schizophrenia experienced priapism, requiring surgical intervention with a shunt for successful resolution.
Area of Science:
- Pharmacology
- Urology
- Psychiatry
Background:
- Alpha-adrenergic antagonists are a known cause of priapism.
- Risperidone, an antipsychotic, possesses alpha-adrenergic antagonistic properties.
- Priapism necessitates prompt medical and potentially surgical intervention.
Observation:
- A 32-year-old male patient with schizophrenia presented with acute, painful priapism.
- The patient was undergoing treatment with risperidone.
- Initial medical management for low-flow priapism proved ineffective.
Findings:
- A diagnosis of low-flow priapism was established.
- Surgical intervention via a proximal corporo-spongiosal shunt (Quackels technique) was performed.
- The surgical procedure resulted in a favorable outcome for the patient.
Implications:
- This case highlights the risk of risperidone-induced priapism.
- Surgical management, specifically the Quackels technique, can be effective for refractory priapism.
- Early recognition and intervention are crucial for managing drug-induced priapism.
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